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Lab-on-chip pharmaceutical synthesis - AskNature

Completely self contained, single chip voice synthesizer and complex sound synthesizer

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Speech Synthesis on a Propeller chip - YouTube

AB - Application specific Network-on-Chip (NoC) architectures have emerged as a leading technology to address the communication woes of multi-processor System-on-Chip architectures. Synthesis approaches for custom NoC must address several requirements including cumulative bandwidth and transaction level (TL) communication requirements, multiple application use-cases, deadlock avoidance, and router port bandwidth and arity constraints. In this paper we present a holistic algorithm for NoC synthesis which is able to address all these requirements together in an integrated manner. The approach is able to generate designs that consume minimum dynamic power consumption, and at most twice the number of routers (and leakage power) as an optimal solution. In terms of performance the technique is able to generate NoC designs with very low average communication latencies (verified by actual simulations) and equally low standard deviation (jitter) while utilizing simple best effort routers. We evaluated the effectiveness and quality of the proposed technique by comparisons with two existing approaches. Extensive experimental results are presented for synthetic/realistic multiple use case applications, cumulative/transaction traffic requirements, increasing application bandwidth requirements, and different port arity constraints.

A Golgi-on-a-chip for glycan synthesis | Request PDF

AB - Oligonucleotide microarrays or oDNA chips are effective decoding and analytical tools for genomic sequences and are useful for a broad range of applications. Therefore, it is desirable to have synthesis methods of DNA chips that are highly flexible in sequence design and provide high quality and general adoptability. We report herein, DNA microarray synthesis based on a flexible biochip method. Our method simply uses photogenerated acid (PGA) in solution to trigger deprotection of the 5′-OH group in conventional nucleotide phosphoramidite monomers (i.e. PGA-gated deprotection), with the rest of the reactions in the synthesis cycle the same as those used for routine synthesis of oligonucleotides. The complete DNA chip synthesis process is accomplished on a regular DNA synthesizer that is coupled with a UV-VIS projection display unit for performing digital photolithography. Using this method, oDNA chips containing probes of newly discovered genes can be quickly and easily synthesized at high yields in a conventional laboratory setting. Furthermore, the PGA-gated chemistry should be applicable to microarray syntheses of a variety of combinatorial molecules, such as peptides and organic molecules.

Hierarchical gene synthesis using DNA microchip oligonucleotides

TI sold its speech-synthesis chip line to Sensory, which discontinued it in late 2007.

N2 - Oligonucleotide microarrays or oDNA chips are effective decoding and analytical tools for genomic sequences and are useful for a broad range of applications. Therefore, it is desirable to have synthesis methods of DNA chips that are highly flexible in sequence design and provide high quality and general adoptability. We report herein, DNA microarray synthesis based on a flexible biochip method. Our method simply uses photogenerated acid (PGA) in solution to trigger deprotection of the 5′-OH group in conventional nucleotide phosphoramidite monomers (i.e. PGA-gated deprotection), with the rest of the reactions in the synthesis cycle the same as those used for routine synthesis of oligonucleotides. The complete DNA chip synthesis process is accomplished on a regular DNA synthesizer that is coupled with a UV-VIS projection display unit for performing digital photolithography. Using this method, oDNA chips containing probes of newly discovered genes can be quickly and easily synthesized at high yields in a conventional laboratory setting. Furthermore, the PGA-gated chemistry should be applicable to microarray syntheses of a variety of combinatorial molecules, such as peptides and organic molecules.

Oligonucleotide microarrays or oDNA chips are effective decoding and analytical tools for genomic sequences and are useful for a broad range of applications. Therefore, it is desirable to have synthesis methods of DNA chips that are highly flexible in sequence design and provide high quality and general adoptability. We report herein, DNA microarray synthesis based on a flexible biochip method. Our method simply uses photogenerated acid (PGA) in solution to trigger deprotection of the 5′-OH group in conventional nucleotide phosphoramidite monomers (i.e. PGA-gated deprotection), with the rest of the reactions in the synthesis cycle the same as those used for routine synthesis of oligonucleotides. The complete DNA chip synthesis process is accomplished on a regular DNA synthesizer that is coupled with a UV-VIS projection display unit for performing digital photolithography. Using this method, oDNA chips containing probes of newly discovered genes can be quickly and easily synthesized at high yields in a conventional laboratory setting. Furthermore, the PGA-gated chemistry should be applicable to microarray syntheses of a variety of combinatorial molecules, such as peptides and organic molecules.

A holistic approach to network-on-chip synthesis — …

Reliable multiprocessor system-on-chip synthesis

Doing the synthesis using a third-party software usually yields better-optimized netlists (put more and/or faster logic into your FPGAs).Place-and-route (P&R) describes several processes where the netlist elements are physically places and mapped to the FPGA physical resources, to create a file that can be downloaded in the FPGA chip.P&R can take a few seconds for a small FPGA, or a few hours for a big one.P&R is always done by the FPGA software from the FPGA vendor, because FPGA vendors do not publish enough information about the internals of their devices to allow any other company to create P&R software.

Application specific Network-on-Chip (NoC) architectures have emerged as a leading technology to address the communication woes of multi-processor System-on-Chip architectures. Synthesis approaches for custom NoC must address several requirements including cumulative bandwidth and transaction level (TL) communication requirements, multiple application use-cases, deadlock avoidance, and router port bandwidth and arity constraints. In this paper we present a holistic algorithm for NoC synthesis which is able to address all these requirements together in an integrated manner. The approach is able to generate designs that consume minimum dynamic power consumption, and at most twice the number of routers (and leakage power) as an optimal solution. In terms of performance the technique is able to generate NoC designs with very low average communication latencies (verified by actual simulations) and equally low standard deviation (jitter) while utilizing simple best effort routers. We evaluated the effectiveness and quality of the proposed technique by comparisons with two existing approaches. Extensive experimental results are presented for synthetic/realistic multiple use case applications, cumulative/transaction traffic requirements, increasing application bandwidth requirements, and different port arity constraints.

me3 synthesis - chips by alecyl on DeviantArt
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  • Synthesis Specialised Software Development

    Chiptune - Wikipedia

  • All About Direct Digital Synthesis | Analog Devices

    We utilize the Agile methodology to solve business and technical challenges facing the financial services industry

  • Answers to some questions about direct digital synthesis (DDS).

    Chip - Wikipedia

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AD9851 Datasheet and Product Info | Analog Devices

N2 - Application specific Network-on-Chip (NoC) architectures have emerged as a leading technology to address the communication woes of multi-processor System-on-Chip architectures. Synthesis approaches for custom NoC must address several requirements including cumulative bandwidth and transaction level (TL) communication requirements, multiple application use-cases, deadlock avoidance, and router port bandwidth and arity constraints. In this paper we present a holistic algorithm for NoC synthesis which is able to address all these requirements together in an integrated manner. The approach is able to generate designs that consume minimum dynamic power consumption, and at most twice the number of routers (and leakage power) as an optimal solution. In terms of performance the technique is able to generate NoC designs with very low average communication latencies (verified by actual simulations) and equally low standard deviation (jitter) while utilizing simple best effort routers. We evaluated the effectiveness and quality of the proposed technique by comparisons with two existing approaches. Extensive experimental results are presented for synthetic/realistic multiple use case applications, cumulative/transaction traffic requirements, increasing application bandwidth requirements, and different port arity constraints.

Synthesis | WARFRAME Wiki | FANDOM powered by Wikia

Released in 1978, the TMC0281 produced speech using a technique called linear predictive coding; the sound emerges from a combination of buzzing, hissing, and popping. It was a surprising solution for something deemed “impossible to do in an integrated circuit,” told IEEE Spectrum. Frantz, one of the four engineers who designed the toy, retired from TI in 2013. Variants of the TMC0281 were used in Atari arcade games and Chrysler’s K-cars. In 2001, TI sold its speech-synthesis chip line to Sensory, which discontinued it in late 2007. But if you ever need to place a very, very-long-distance phone call, you can find Speak & Spell units in excellent condition on eBay for about US $50.

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