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Recent Advances in the Synthesis of Well-Defined Glycopolymers.

T1 - Multistep synthesis of the SrFeO2F perovskite oxyfluoride via the SrFeO2 infinite-layer intermediate

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Synthesis of Functionalized Bisphosphonates via Click Chemistry.

S.; Kajiki, R.; Hanatani, H.; Kong, X.; Ozoe, F.; Matsui, Y.; Matsumura, F.; Ozoe, Y., Synthesis and Structure-Activity Relationships of 1-Phenyl-1-1,2,3-triazoles as Selective Insect GABA Receptor Antagonists.

Sonication-Assisted Library Synthesis of Oxazolidinone-Carbohydrate Conjugates.

R., Activity-Based Protein Profiling Reagents for Protein Arginine Deaminase 4 (PAD4): Synthesis and in vitro Evaluation of a Fluorescently Labeled Probe.

Synthesis and Versatile Reactions of β-Azidotetraarylporphyrins.

Photovoltaic Properties of New Cyanine-Naphthalimide Dyads Synthesized by 'Click' Chemistry.

I.; Scheel, A.; Komber, H.; Maier, G.; Zech, C.; Hawker, C., Potential of cycloaddition reactions in the synthesis of hyperbranched polymers of different degree of branching.

A.; Hocquemiller, R., Annonaceous acetogenins: The hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent Squamocin analogues.

Synthesis of New Substituted Lactones by "Click" Chemistry.

Copper-Catalyzed Synthesis of -Sulfonyl-1,2,3-Triazoles: Controlling Selectivity.

The module is constituted of a series of laboratory activities designed to familiarise students with an array of techniques centred around key aspects of inorganic syntheses. Specifically, the module emphasizes stability and speciation methods and their applications to the inorganic chemistry field. All aspects of the module will be supported by associated relevant analytical technologies.

Through the use of modern molecular biology techniques, it is possible to transfer individual enzymes from their host organism and produce them in more amenable laboratory strain bacteria. This allows them to be more easily studied, engineered and integrated into new enzyme cascades, both in whole cell systems and as cell-free formulations. In the Flitsch group we are interested in the tailoring of various enzymes to perform specific, synthetically-useful reactions and incorporating these into bespoke pathways for the production of industrially- and biomedically-relevant compounds. Examples of target products of particular interest include high value chiral amines as pharmaceutical / fine chemical precursors and glycoconjugates as chemical biology probes for glycobiotechnology.

Synthesis of Saccharide-Terminated Poly(ε-caprolactone) via Michael Addition and 'Click' Chemistry.
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  • Modular Synthesis of ABC Type Block Copolymers by "Click" Chemistry.

    KW - Multistep synthesis

  • Synthesis of Triazole-Linked Pseudo-Starch Fragments.

    The Potential of Cycloaddition Reactions in the Synthesis of Dendritic Polymers.

  • Synthesis of Cyclo-PMMA via Click Chemistry Combined with ATRP.

    Synthesis of Peptide-Based Polymers by Microwave-Assisted Cycloaddition Backbone Polymerization.

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Synthesis of Lanthanide(III) Chelates by Using 'Click' Chemistry.

This module aims to provide deeper understanding on physicochemical principles behind materials and their properties, exploring advanced concepts in supramolecular chemistry and synthetic routes for more complex organic molecules. Crystals, colloids, discontinuous phases and solid state chemistry concepts are studied in depth to understand physical and chemical properties that give these materials a wide range of application in industry and research.

Synthesis of Ferrocene-containing Polyacetylenes by Click Chemistry.

This module aims to provide deeper understanding on physicochemical principles behind materials and their properties, exploring advanced concepts in supramolecular chemistry and synthetic routes for more complex organic molecules. Crystals, colloids, discontinuous phases and solid state chemistry concepts are studied in depth to understand physical and chemical properties that give these materials a wide range of application in industry and research.

Design and Synthesis of Triazole-Based Peptide Dendrimers.

This module covers in greater depth the thermodynamics and kinetics of processes occurring on solid surfaces. Heterogeneous catalysis is used as an example of how reactions at solid surfaces differ from those in the bulk. Electrochemistry is further developed. Organic chemistry topics are the advanced areas of radical chemistry and orbital symmetry along with heteroelement and organometallic synthesis. Concepts of supramolecular chemistry are covered.

ConCept: de Novo Design of Synthetic Receptors for Targeted Ligands.

This module covers in greater depth the thermodynamics and kinetics of processes occurring on solid surfaces. Heterogeneous catalysis is used as an example of how reactions at solid surfaces differ from those in the bulk. Electrochemistry is further developed. Organic chemistry topics are the advanced areas of radical chemistry and orbital symmetry along with heteroelement and organometallic synthesis. Concepts of supramolecular chemistry are covered.

Click Synthesis of Fluorine-Rich Cyclotriphosphazene Hydrazones.

The concept of this module is to offer students the opportunity to experience and dissect the process of designing a material which fulfils specific requirements or needs, its synthesis and its characterisation.
Through this process, the module offers the opportunity to host advanced complex organic syntheses (such as asymmetric synthesis) and supramolecular synthesis.

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