What is Monro-Kellie hypothesis? - Health and USMLE …
The Monro-Kellie hypothesis
What is Monro-Kellie hypothesis
Rabak-Wagener, Eickhoff-Shemek, and Kelly-Vance(1998) studied the effects of unrealistic body shapes in magazines oncollege-age women in “The Effect ofMedia Analysis and Behaviors regarding Body Image Among College Students.” They also sought to discover whetheror not a media analysis program helped young women change their attitudes andbeliefs about body image. The fist method they used was a survey to measurerespondents’ beliefs and behaviors regarding fashion-advertising images. Afterthe survey, the large group was then split into a comparison and anintervention group. The intervention group participated in a 6.5-hour programanalyzing, critiquing, and learning about the fashion industry and theirmethods of advertising. After the program both groups were surveyed again. Onthe pre-test there was no significant difference between the intervention andcomparison groups. On the post-test, however, students in the interventiongroup reported significant changes in their perceptions of body image while thecomparison group reported no significant changes. This study and its findingsare important because they suggest that magazines do influence the way womenfeel about their bodies. The study is also somewhat encouraging because itsuggests that media analysis can be a valuable tool in changing college-agewomen’s beliefs about the ideal body.
The average intracranial volume in the adult is approximately 1700 mL, composed of the brain (1400 mL), CSF (150 mL), and blood (150 mL). Basic to an understanding of the pathophysiologic changes related to ICP is the Moro-Kellie hypothesis. It states that the skull, a rigid compartment, is filled to capacity with essentially noncompressible contents – brain and interstitial fluid (80%), intravascular blood (10%), and CSF (in the ventricles and subarachnoid space; 10%). The volume of these three components remains nearly constant in a state of dynamic equilibrium. If the volume of any one component increases, another component must decrease reciprocally for the overall volume and dynamic equilibrium to remain constant. If the volume of any one component increases with a reciprocal decrease in one of the other components, ICP will rise. This hypothesis applies only when the skull is fused (i.e., a closed box).
Monro-Kellie hypothesis. - YouTube
However, the amount of displacement of the brain, CSF, or blood that can occur through compensatory mechanisms is limited. After compensatory mechanisms have been exceeded, ICP rises and intracranial hypertension results. Specific medical therapies that have been used to maintain the intracranial volume in a steady state include the following:
Intracranial hypertension usually is problematic in the first 2 to 3 days post injury but may not become so until a week later.The Monroe Kelly hypothesis states that the total volume of the intra cranial contents, Vt, is equal to the sum of its contents;Vt = Vcsf + V blood + V brain.Initially after a head injury, with brain swelling or bleeding, the CSF is displaced from the skull.
The Monro-Kellie doctrine states that three things exist ..
According to the Monro-Kellie hypothesis, reciprocal compensation occurs among the three intracranial components – brain tissue, blood, and CSF – to accommodate any alterations within the intracranial contents. The compensatory mechanisms that maintain the intracranial volume in a steady state include the following:
Describe the 4 methods of intracranial pressure monitoring
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