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Reduction generated between amino benzene (A) acid.


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3-NITROBENZOIC ACID; 121-92-6; M ..

Y Hasegawa, et al. A novel degradative pathway of 2-nitrobenzoate via 3-hydroxyanthranilate in Pseudomonas fluorescens strain KU-7.FEMS Microbiol Lett.,2000,190(2), 185-190.Smith, G, et al. Molecular adducts of 2,6-diaminopyridine with nitro-substituted aromatic carboxylic acids and the crystal structure of the 1:1 adduct of 2,6-diaminopyridine with 2-nitrobenzoic acid.Australian Journal of Chemistry.,1999,52(1), 71-74.

3-Nitrobenzoic acid - Wikipedia

Smith, G, et al. Molecular adducts of 2,6-diaminopyridine with nitro-substituted aromatic carboxylic acids and the crystal structure of the 1:1 adduct of 2,6-diaminopyridine with 2-nitrobenzoic acid.Australian Journal of Chemistry.,1999,52(1), 71-74.

4-Nitrobenzoic acid may biodegrade in soil based on 62% ..

Examples of displayed formula of aromatic compounds, graphic formula, molecular formula, skeletal formula, structural formula of aromatic hydrocarbons (arenes like benzene and methylbenzene), aromatic halides, phenols, aromatic aldehydes, aromatic ketones, aromatic carboxylic acids and derivatives, primary aromatic amine, secondary aromatic amines, tertiary aromatic amines, aromatic amides, diazonium Salts and azo dyes , nitro-aromatics, aromatic sulphonic/sulfonic acids .

Ahmed M. Tafesh was born in 1957 in Acre, Israel, and following his arrival in the United States in the fall of 1977, he received his B.S. degree in chemistry at Portland State University in 1981. In 1984 he received his M.S. at Oregon State University in the area of physical organic chemistry working on mechanistic investigation of conjugated carbenes with Professor Peter Freeman. He then moved east to Salt Lake City, where he received his Ph.D. in the area of free radical methodology development as well as the total synthesis of pseudomonic acid under the supervision of Professor Gary Keck. After graduation in 1989 he joined Hoechst Celanese Corp. in Corpus Christi, TX, as a Research Chemist working in exploratory research. In 1991 he was promoted to Research Chemist II and worked on the development of pharmaceutical intermediates. In 1993 he was promoted to Senior Research Chemist and in 1994 he was awarded a two year assignment in Hoechst AG Corporate Research in Frankfurt, Germany. In Germany, Ahmed was active in the area of development of oxidation reagents as well as the development of water soluble catalysts for the reductive carbonylation of aromatic nitro compounds. Ahmed holds more than 20 patents in different areas. Upon completion of his assignment, Ahmed will return to Texas for his new role as a group leader in the area of asymmetric catalysis.

m-Nitrobenzoic Acid Benzoic acid, m-nitro-Oliver Kamm, ..

Rappeport & Bunn (1994) suggested that aplastic anaemia in humans is an idiosyncratic reaction to chloramphenicol, which has an immunological basis and which is related to the nitrobenzene structure. This hypothesis is supported by clinical evidence showing that 40-50% patients with aplastic anaemia have a partial or complete response to a variety of immunosuppressive agents.

The biosynthetic route of chloramphenicol starts with the general shikimate pathway for assembling aromatic structures. It then branches at chorismic acid to generate ­amino-phenylalanine, which serves as an advanced precursor of the ­nitrophenylserinol moiety of chloramphenicol (He et al., 2001; Lewis et al., 2003). 3’--Acetyl-chloramphenicol, which is commonly formed from chloramphenicol by many resistant bacteria, has also been isolated from the antibiotic-producing organism. It has been suggested that it is a protected intermediate in chloramphenicol biosynthesis, implicating acetylation as a self-resistance mechanism in the producing organism (Gross et al., 2002). 3’--Acetyl-chloramphenicol esterase activity was detected in cell-free extracts of strains of other spp. and var. , which produced chloramphenicol (Nakano et al., 1977).

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  • Synthesis of 2-chloro-5-nitrobenzoic acid - …

    m-Nitrobenzoic acid

  • Preparation of 2-chloro-5-nitrobenzoic acid


  • 3-Nitrobenzoic acid (9CI) Known Uses

    m-Nitrobenzoic Acid.

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Synthesis of 3-hydroxy-4-nitrobenzoic acid - …

The Food and Drug Administration of the USA has published an environmental assessment of chloramphenicol in the context of a proposal made in March 1985 to withdraw approval of new animal drug applications (NADAs) using chloramphenicoloral solution (Food and Drug Administration, 1985). Further information was obtained from the Hazardous Substances Databank, a database of the National Library of Medicine's TOXNET system (Hazardous Substances Databank, 2003). The information available from these sources (most of the original literature cited was not available for this review) is summarized as follows. The solubility of chloramphenicol in water at 25°C is 2.5 g/l over a wide range of pH. Chloramphenicol is not adsorbed to clay or soil to any significant degree and therefore has very high mobility in soil. Adsorption to sediment and bioconcentration in aquatic organisms should not be important processes. Chloramphenicol is degraded by biological, chemical, and photolytic means and undergoes oxidation, reduction and condensation reactions upon exposure to light in aqueous solution. Photochemical decomposition of chloramphenicol in vitro by ultraviolet-A (UV-A) light leads to the formation of ­nitrobenzaldehyde (pNB), ­nitrobenzoic acid (pNBA) and ­nitrosobenzoic acid (pNOBA); the latter comprises up to 45% by molarity of the starting amount of chloramphenicol (de Vries et al., 1994).

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